About

/About
About 2018-01-25T15:06:54+00:00

Project idea

As a consequence of the ageing of the society, osteoporosis (literally “porous bone”) and its  complications is becoming more and more prevalent, making the bone disease a health priority in many parts of the world. Currently osteoporosis is commonly known as a “silent killer” disease. Usually osteoporosis manifests itself in a drastic manner, i.e. through fracture of the osteoporotic bone in the affected individual. Until now little or no measures for prevention or early detection of this disease are taken, because no simple, yet sufficiently precise or sensitive tools for early detection of individuals at risk of osteoporosis are available.

The overall objective of the currently proposed PoCOsteo project therefore is the development, clinical validation and preparation for commercialisation of a Point-of-Care tool for bone disease (a.o. osteoporisis) prevention, detection and treatment.

Analysis

To realize this objective a balanced consortium of 5 research partners and 3 SME’s has been brought together, and a well considered workplan devised. Two TRL3 technologies for individual proteomic and genomic electrochemical sensors, available from 2 consortium partners will form the base of the developments. The sensors will be further optimised, combined in a single microfluidic cartridge and integrated in a complete and  independent point-of-care bone health assessment tool. The tool will consequently be clinically validated in 2 hospitals (Graz and Tehran), and a business plan for a commercial start-up company wil be prepared for the intended valorisation of the technical and medical activities. The aim is to reach a TRL6 / TRL7 for the complete tool and for the combined microfluidci cartridges. The project will be supported and advised by the IOF, the International Osteoporosis Foundation, which is the main global alliance of patient societies, research organizations, healthcare professionals and international companies working to promote bone, muscle and joint health.

As a consequence of the ageing of the society, osteoporosis (literally “porous bone”) and its  complications is becoming more and more prevalent, making the bone disease a health priority in many parts of the world.

Currently osteoporosis is known as a “silent killer” disease.

Research

the proof of concept of different parts of the final device are already designed in the lab

Development

integrate proteomics and genomics technology into a functional single PoC device

Analysis

comparing the results with that of the current state-of-the-art of each technology separately

Commercialisation

Preperation for commercialisation of the tool to identify individuals at high-risk of osteoporosis and osteoporotic fracture.

Discover The Future

We are a multi-disciplinary team committed to create a Point-Of-Care tool for bone disease, prevention, detection and treatment.

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